Posted by Rotunda Scientific on Sep 04, 2025
The ESR5000 (formerly MS-5000) is a compact, benchtop Electron Spin Resonance (ESR), also known as Electron Paramagnetic Resonance (EPR) spectrometer, designed for powerful performance, accuracy, and ease of use in research and industrial settings.
The ESR5000 is widely used as a complete alanine–EPR dosimetry system, ideal for routine dose verification in industrial irradiation facilities or in-house calibration labs. It delivers stronger signal sensitivity than typical benchtop units and reduces measurement times to less than 10 seconds, providing reliability and fast throughput.
Increasingly employed in environmental science, the ESR5000 measures free radicals in airborne particulates, water, and soil. This includes environmentally persistent free radicals (EPFRs) and other oxidants that affect the environment and human health. It supports research into particulate chemistry and oxidative stress in environmental samples.
The system finds application in bioinorganic and polymer chemistry, enabling study of radicals in coordination chemistry, catalysis, Fenton reactions, and material degradation. It’s used to analyze asphaltene content in crude oil, UV-stability of polymers, varnish coatings, semiconductors, and more.
Researchers use ESR to detect reactive oxygen and nitrogen species (ROS/RNS), nitric oxide, and radical-generating systems, as well as spin-labeled biomolecules (DNA/RNA, enzymes, proteins). ESR5000 enables insights into oxidative stress, enzyme mechanisms, membrane dynamics, and clinical diagnostics.
From assessing antioxidant content in foods and beverages to evaluating UV-filter efficacy in cosmetics, the ESR5000 helps quantify radicals post-irradiation or storage. It also supports pharmaceutical QC by profiling paramagnetic impurities, evaluating stability, and monitoring sterilization effects.
Compact and Mobile: Benchtop footprint (~40 x 26 x 20 cm), weighing ~45 kg—fits easily into crowded labs or mobile setups.
High Sensitivity & Stability: X-band operation with detection sensitivity down to ~5 x 10^9 spins/G and high signal-to-noise (>600:1).
Extreme Temperature Flexibility: Optional accessories support measurement temperatures from 77 K to +473 K.
User-Friendly Software: ESRStudio software enables intuitive operation and automated analysis—ideal even for users without prior spectroscopy expertise.
Low Maintenance, High Uptime: Auto-calibration and solid-state design offer >99% uptime.
Learn More about the ESR5000 Here
This article was written in part with the assistance of AI to help organize, summarize, and reference publicly available information.
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